[Evaluating the relationship of the pre-term, method of delivery and breastfeeding with asthma]

Asthma is the most common chronic disease in children. The aim of this study was to investigate the relationship between pre-term delivery and breastfeeding with asthma. We studied 228 asthmatic patients who were referred to the Allergy Department in Children's Medical Center [Tehran]. Asthma was diagnosed based on the history, physical exam and dspirometery [if possible] by an allergist. Pre-term and method of delivery was on delivery card and breastfeeding duration [divided 6 months or more], was based on Mothers statement to gain data and was analyzed by T-test. 228 asthmatic patients [aged 5-17 years] of whom were 132 Males and 96 Females. 216 cases were term and 12 cases pre-term. Exclusive breastfeeding duration for at least 6 months was reported in 183 cases. Cesarean section was in 78 cases [34.22%], while normal delivery was observed in 150cases [65.78%]. In this study, breastfeeding [at least 6 months] and normal delivery can be decreased by asthma; however, pre-term delivery was not affected by the asthma prevalence

Adverse reaction following intravenous immunoglobulin in primary immunodeficiency patients

Intravenous immunoglobulin is used for primary immunodeficiency disorders. There have been some reports that intravenous immunoglobulin causes side effects. The aim of this study was to investigate intravenous immunoglobulin side effects in immunodeficiency patients. The study utilized the data of 29 primary immunodeficiency patients that were referred to allergy and immunology department in Medical Children Center in Tehran. 29 patients having completed record data files in the hospital, were the subjects of this study. Of 29 immune deficiency patients [aged 15 months to 55 years], they were 19 Males [65/51%] and 10 [34/48%] Females. Prevalence of disorders include common variable immunodeficiency 16 [55/17%], Bruton disease 8 [27/58%], hyper IgM 4 [13/79%] and severe combined immunodeficiency 1 [3/44%]. Based on the recorded data, the duration of infusion has been 5 months to 15 years. 15 patients had reported side effects [51/72%]. 34 infusions from the total of 1,626 infusions accompanied with side effects [2/09%]. Most side effects were occurred during 30 minutes onset of infusion and most were caused by rapid infusion. Most side effects were mild reactions [fever, chills and ...]. Intravenous immunoglobulin is a rather safe drug with mild side effects. With an appropriate technique and proper infusion, these side effects can be reduced

Common food allergens in Iranian children

The prevalence of food allergy is different in different parts of the world. Identification of the most common food allergens is a priority in any population to provide effective preventive and curative measures. The aim of this study was to determine the most common food allergens in Iranian children. One hundred and ninety children with skin, respiratory or gastrointestinal symptoms, thought to be due to food allergy, were studied. The total serum IgE and eosinophil count tests were measured in all patients. Allergy to 25 food allergens was determined according to the patient's history, skin prick tests, RASTs [Radioallergosorbent Test] and open food challenge tests. Findings: The most common food allergens were cow's milk, tomato, egg white, egg yolk, beef and almond, respectively. The order of common food allergens in this study was different from other reports; this might be due to the different food habits and /or ethnic diversities